Web Avatars: Erasmus and Kinkajou 
Web Avatars: Erasmus and Kinkajou 
Erasmus: Epilepsy is variously called fits, funny turns, febrile convulsion children or blackouts. Many doctors believe that unstable neurones at the sites of injury are responsible for the hyperexcitable focus causing the fit. Usually no cause for the focus of cerebral injury is ever found. The significance of symptoms under the Paill Spectrum model is discussed.
This web page Discusses a new theory to explain epilepsy occurrence. (The Paill Spectrum model of disease).
DR Xxxxx: Epilepsy may be known as grand mal, petit mal, absence seizures, partial seizures, or fits. Brain scars are blamed often. Many victims often undergo extensive investigations (CT, EEG, MRI), to exclude the presence of a brain tumour or brain scar, usually not found. New investigations such as MRI often lead o the discovery of brain ghosts on scan which may be representative of MS = , Multiple Sclerosis lesions. The Paill Spectrum model proposes new alternative prophylactic treatments for illness and suggests that other disease modifying treatments may be possible. Typical standard treatments include, Dilantin, phenytoin, Tegretol, Epilim, Valproate, Sabril. These treatments are in no way excluded as part of a therapy programme in the Paill Spectrum model. Once brain injury and scarring occurs, it is essential to control unstable loci of neurones and medication is the mainstay of this activity.
Paill Spectrum proposes that there may be preventative or antideterioration strategies possible. Medications currently used control disease but are not thought to modify disease progression. First time epileptic fits are recommended to undergo an extensive assessment process to exclude macroscopic disease processes which may need to be treated in their own right. e.g. A tumour causing epilepsy needs to be treated as a tumour, not just as epilepsy. Paill Spectrum typically causes only microscopic brain lesions. These lesions may be modified in extent and severity due to the presence of other diseases as modifying cofactors.
The Paill Spectrum model suggests that other symptoms such as chronic fatigue, sweaty hands, dizziness, or loss of balance, aches and pains may be associated. The Paill Spectrum model of disease also proposes a definition of the illness in terms of symptoms, signs, investigations and response to treatment. Download the clinical assessment file from the Download Page.
DR Xxxxx : Odd Events in Life
Perhaps a First or Second Wave Paill Spectrum Phenomenon
Current medical opinion on an episode of "first time" epilepsy is that this does happen, usually for no reason. While in some patients infections, trauma, birth injury or cancer may be responsible for a first fit, there is no obvious cause found in many patients. Sometimes irregularly, fever will trigger epilepsy in a child, but little is known about this phenomenon.
A patient who has had a first time epileptic fit, may often be witnessed in having the fit. An ambulance will usually be called by concerned relatives or bystanders. The patient will go to hospital and be seen in Casualty or the Emergency Department. A history and clinical examination will be done by the Casualty doctor, usually finding that there is no reason for the fit to have occurred. Next some blood tests will be taken. Back To Epilepsy Top
A typical test sequence would be :
DR Xxxxx : Long term the patient is discharged with nothing found. The Casualty doctor may start the patient on anti-epileptic medications if they are worried about the patient or if they are being extra careful.
The entire process covers many different body organs and tests for many possible diseases. Strangely, in the majority of people, nothing is found. Even the EEG is usually normal. Not only that, but in well patients who have never had a fit, the EEG may well be abnormal while in sick patients who have had a fit, the EEG may well be normal. The specialist may order a CT scan (often for cost containment reasons), and again this is often normal as well . Back To Epilepsy Top
The specialist if concerned may then order an MRI and here's finally where things might get interesting. Sometimes the MRI (A picture type of test giving a cross-sectional image of the brain, but done with magnets not with X-rays), finds odd white bits in the brain. Strangely, these may eventually disappear with nothing found on follow up MRIs. Doctors will then usually discount the finding, as "How can anything important just go away?"
Kinkajou : So what does the PaillSpectrum "model" tell us about what is going on? DR Xxxxx : Nothing happens for no reason, but lots of things including epilepsy may happen for no obvious reason.
Paill Spectrum is a very quiet illness indeed. Paill Spectrum rarely causes scarring, but can occasionally cause areas of micro-damage (micro-necrosis), under unusual circumstances. This type of injury is most likely to be symptomatic in critical function sites, such as the brain. This is probably what is happening when the "white ghosts" on MRI are seen and disappear. The Paill Spectrum immune flare has arrived, cleaned up the affected area and then everything has settled down. In the very occasional patient there is scarring and long term irritation of some neurones. A hyperexcitable focus may set itself up and lead to occasional epileptic attacks.
The Paill Spectrum model would therefore suggest a possible mechanism for the development of epilepsy, in people with no obvious cause or reason visible , to explain why this happened (epilepsy) to the patient. Back To Epilepsy Top
There are clinical tests and blood tests that can confirm the presence of Paill Spectrum Illnesses. The knowledge of the illness is very new and doctors are not accustomed to searching for evidence of the illness. If they are motivated by concern for the patients welfare, they would see responses to Paill Spectrum antibiotic therapy on the MRI, blood tests and in their assessments of clinical symptoms. It is not a hard condition to diagnose, or partially treat, but it is a condition that very few doctors are even looking for, or have heard of at this time. (Hence the role of the web site).
Normal medicine has no answer to the question to why things like attacks of epilepsy "out of the blue" happen. Normal medicine just states that epilepsy just does happen, usually for no obvious cause and that's all. An Act of God, if you will. Perhaps there may indeed be a cause in some patients. perhaps a Paill Spectrum cause? Back To Epilepsy Top
Once a focus of injury has formed , giving rise to a hyperexcitable focus of nerve tissue, there is no guarantee that the focus can be cured with Paill Spectrum therapy. The model would suggest that it is more likely that future disease progression, may be stabilised rather than a cure occurring.
Kinkajou: If Paill Spectrum May Cause Epilepsy, DR Xxxxx :There is another Syndrome that would be expected on the basis of this clinical case scenario. This syndrome is typified by Irritability, Fatigue and episodes of recurrent neurological injury. Doctors often see the early phase of this type of illness to date with the "MRI ghosts" appearing. Most commonly, their significance is regarded as uncertain. So, the answer as to whether this is a Paill Spectrum Illnesses, lies with researchers in the future. Strangely though, one doctor I know relates seeing one segment on a TV Current Affairs program where a doctor suffering from this syndrome had done his own research on the illness. The doctor on TV had discovered that nutritional therapy could make a difference to the illness. Dr. Xxxxx recognised the strong parallels between the type of nutritional therapy this doctor was using and the types of nutritional therapy that are useful in the Paill Spectrum treatment model.
DR Xxxxx : The Paill Spectrum Model of First time Epilepsy Paill Spectrum symptoms are likely to be present depending on the age of the patient. Symptom profiles vary depending on the patient's age. Sweaty hands for example, are much more common in younger ages, and tend to be rare in patients over 50 years of age. Back To Epilepsy Top
Blood test results will show typical Paill Spectrum result patterns.
In addition, other test results may give further information. As mentioned, occasionally, an MRI may show "white ghost lesions" scattered throughout the brain. These probably represent a microinfarct pattern of immune response, as distinct to the typical usual apoptotic (non-scarring) immune response that seems to occur in most Paill Spectrum infections.
Very early infections with Paill Spectrum such as occurring in utero, will cause substantial damage to babies. As the baby’s immune response is reduced and as antibodies are only partially protective in Paill Spectrum infection, extensive damage to the child is likely. This will likely present as extensive developmental delays, spasticity and if acute may cause events such as cerebral oedema in the post partum period. Long-term epileptic events may be seen if irritation occurs through micro-inflammatory foci, if scarring occurs or if there is extensive loss of local inhibitory neurones. Back To Epilepsy Top
DR Xxxxx : Older people are also prone to these "first" epilepsy events.Fever, often is associated with increased Paill Spectrum Immune reactions and is likely to trigger damage “crises”. When the body is hyperthermic, or feverish, immune reactions may be accelerated. Instead of a gradual process of cell death via apoptosis ( cells die one by one), a chunk of tissue may be affected and may even be entirely destroyed by the immune reaction. This damaged "focus" when found in nerve type tissues can scar and lead to the formation of permanently irritated scars or "foci". This irritation or excitation of the focus of nerves at the edge of the scar, forms a potential source for a wave of nerve triggerings. The process could be likened to the "Mexican Waves" we see form in the grandstands at a football game, when the crowd becomes too hyped up.
Our staff may have more to share. Click our donation button if you are willing to help us help you. If you support us ,we can keep working for all our sakes.Paill Spectrum initiated damage following a more intense immune reaction which may be triggered by heat or other factors; may be the main cause of these idiopathic (no cause) "first time" epileptic events in children. As a rule, these types of immune events are rare for Paill Spectrum infection, in the PaillSpectrum disease model.
Dr. Xxxxx has been able to undertake only partial follow up of early cases in his practice, so the role of Paill Spectrum in epilepsy including early epilepsy is suggested currently more by theory than by experience. Back To Epilepsy Top
DR Xxxxx : Markers of Paill Spectrum Infection in Idiopathic EpilepsyThe Paill Spectrum model proposed by Dr. Xxxxx says that many idiopathic types of epilepsy may result following infection with the Paill Spectrum organism. The presence of the organism is associated with other characteristic symptoms unique to the Paill Spectrum organism. These other symptoms will also improve subtly and slowly but definitely with Paill Spectrum treatment.
Erasmus: It is critical to treat people with effective therapy, not just symptomatic antiepileptic medication, or drugs. Medicine for “symptoms” does not change the progress of the disease. Anti-epileptic medications stop the spread of "Mexican Waves" of nerve triggering by calming the nerves down. In the PaillSpectrum model, it becomes obvious that this type of treatment is important to control the patient's symptoms, but does nothing to change the progression of the disease process that caused the formation of the epileptic focus, in the first place. If Paill Spectrum caused the damage that caused the epileptic focus to form, anti-epileptic treatment will not stop further damage occurring, but it will help to stop further symptoms appearing. :-] Back To Epilepsy Top
DR Xxxxx: Common medications used to treat epilepsy include:Phenytoin (Trade Name: Dilantin), Carbamazepine (Trade Name: Tegretol), Sodium Valproate (Trade Name : Epilim), Gabapentin (Trade Name : Sabril), Tiagabine ( Trade Name: Gabatril), Levetiracetam (Trade Name: Keppra), Lamotrigine (trade Name Lamictal),Pregabalin (Lyrica),Primidone (Trade Name : Mysoline), Sulthiame (trade Name Ospolot), Clonazepam (Trade Name : Rivotril),Phenobarbitone, Topiramate (Trade Name: Topamax), Oxcarbazepine (Trade Name: Trileptal), Ethosuximide (Trade Name: Zarontin).
Every medication has only one generic name but can Have many Trade Names. The Trade Name is the name under which a particular pharmaceutical company markets its product. e.g. Paracetamol can be marketed as Panadol or as Panamax. Although the active ingredients of medications can be the same, the method of pressing these into a tablet or capsule can vary as can the excipient. Excipients are: the other ingredients mixed with the active ingredient to make up a capsule or tablet. (Excipients are important to make a medication dose big enough to pick up with fingers, to help absorption of a medication or to minimise irritation effects on the stomach lining).
Back To Epilepsy Top
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DR Xxxxx : Prognosis for Patients with Idiopathic Epilepsy in the Paill Spectrum ModelPaill Spectrum will not kill you. It can and does cause progressively more symptoms with time. Paill Spectrum is perhaps better thought of as a lifestyle threatening illness, rather than a life threatening illness.
There is no magic cure for people who have a long history of epilepsy. Damage has already been done. The important goal is to stop further damage from being done. Without treatment , Paill Spectrum continues to progress. If Paill Spectrum is involved in the genesis and progression of "idiopathic" epilepsy, treatment of the Paill Spectrum infection should prevent a deterioration of intensity of the symptoms.
Paill Spectrum treatment comes as a package deal. All of the types of nutritional and antibiotic therapy are critical to the long-term treatment success. Bizarre events may occur with treatment, though predominantly with second line therapies. The therapies promoted on this web site are freely promoted because they are the safest first line treatments that can change the course of the Paill Spectrum Illnesses causing the symptoms. With epilepsy, it is likely that the second line antibiotics will need to be used to achieve symptom response. The Paill Spectrum model of disease as developed by Dr. Xxxxx suggests that these are often signposts on the road to recovery, not reasons to abandon treatment.
If you have epilepsy, it is important to continue to take your anti-epileptic medications. They can prevent further fits and long-term consequences of having further fits such as loss of a license, having an accident and most importantly injuring oneself or others. Epilepsy is one of the circumstances where it is critical to continue taking your symptomatic antiepileptic medications.
However, there may be other options in treatment. Even if doctors are unwilling to be involved in a Paill Spectrum therapy program, basic nutritional changes can produce dramatic illness response in up to about 1/3 of patients using nutritional therapy alone. :-} Back To Epilepsy Top
Go to Treatment Page
DR Xxxxx: The Next Phase of the Progression of a Long Term, Paill Spectrum Illnesses Causing Epilepsy may involve:
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Beethoven and Frobisher : The conclusions arising from the Paill Spectrum model of disease as pioneered by Dr. Xxxxx, implies that the causation of many medical conditions varies substantially from current medical thinking. Until research and further assessment of these concepts validates the concepts proposed, you must make your own mind up about what treatment regime you follow. Paill Spectrum therapy gives distinct identifiable and measurable feedback to patients, their carers, and treating doctors at every step of a therapy cycle.
Dr. Xxxxx has not treated epileptic patients for Paill Spectrum, but the Paill Spectrum Model would predict that cases of injury related epilepsy would arise.
Symptoms of Paill Spectrum may improve to an extent discernible to everyone usually starting from within two weeks of initiation of the treatment cycle. If epilepsy is prevented, symptomatic improvements may be as subtle as no further fits noticed in the next few years. It is easy to see an improvement in someone having lots of fits. Once damage is done, these are unfortunately, the type of patients in whom an improvement in symptoms may be the hardest to discern. Symptoms may well continue. A good result in these patients, is a reduction in "progression" of the illness. Yes you have epilepsy, but no it is unlikely to get worse over the next ten years.
Back To Epilepsy Top
The symptoms are likely to recur or reflare in some patients in three to nine months, if underlaying nutritional risk factors remain unchanged or if Paill Spectrum therapy is ceased.
How about men's erection problems. Are they just due to loss of interest?.
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DR Xxxxx : This web page Discusses a new theory to explain epilepsy occurrence. (The Paill Spectrum model of disease). Epilepsy may be known as grand mal, petit mal, absence seizures, partial seizures, or fits. Brain scars are blamed often. Many victims often undergo extensive investigations (CT, EEG, MRI), to exclude the presence of a brain tumour or brain scar, usually not found. New investigations such as MRI often lead o the discovery of brain ghosts on scan which may be representative of MS = , Multiple Sclerosis lesions. The Paill Spectrum model proposes new alternative prophylactic treatments for illness and suggests that other disease modifying treatments may be possible. Typical standard treatments include, Dilantin, phenytoin, Tegretol, Epilim, Valproate, Sabril. These treatments are in no way excluded as part of a therapy programme in the Paill Spectrum model. Once brain injury and scarring occurs, it is essential to control unstable loci of neurones and medication is the mainstay of this activity.
Paill Spectrum proposes that there may be preventative or antideterioration strategies possible. Medications currently used control disease but are not thought to modify disease progression. First time epileptic fits are recommended to undergo an extensive assessment process to exclude macroscopic disease processes which may need to be treated in their own right. e.g. A tumour causing epilepsy needs to be treated as a tumour, not just as epilepsy. Paill Spectrum typically causes only microscopic brain lesions. These lesions may be modified in extent and severity due to the presence of other diseases as modifying cofactors.
The Paill Spectrum model suggests that other symptoms such as chronic fatigue, sweaty hands, dizziness, or loss of balance, aches and pains may be associated. The Paill Spectrum model of disease also proposes a definition of the illness in terms of symptoms, signs, investigations and response to treatment. Download the clinical assessment file from the Download Page.
Our staff may have more to share. Click our donation button if you are willing to help us help you.
If you support us ,we can keep working for all our sakes.
Our staff may have more to share. Click our donation button if you are willing to help us help you.
If you support us ,we can keep working for all our sakes.
Erasmus : Epilepsy is a condition that is well known to people and their medicos. However, there is no cause. Paill Spectrum is proposed as a cause on this page. Paill is a neurotropic agent with substantial effects on behaviour through progressive brain injury.
It would seem logical to find this condition associated with the genesis of epileptiform foci within the brain.
DR Xxxxx : It is very hard to make observations on the progress of any brain injury. Poor access and the microscopic nature of most brain injury makes it impossible to image or detect damage in progress. Even when damage is found, it is unlikely to be amenable to investigation which may reveal the true nature of then damage process. Ie No one in their right mind would do a biopsy.
But, there are other ways to reveal association. Intensive therapy for Paill with blood brain barrier penetrating agents may completely alter the way we treat this group of conditions in the long run.
DR Xxxxx : The situation is made more complex because
CENSORED ref AX4006 by order of “Frobisher” authorised by “The Commandant”.
Doctors would argue that much is known about this group of conditions.
Dr Axxxx : Yet they don't know the why and the how. They can't even understand where their learnedness and their knowledge of double blind randomised controlled trials lets them down. The medical world is an apprenticeship. It guarantees stupid ideas get promulgated. It ensures no one rocks the boat. How can you be right when we all agree any dissenting opinions are wrong?